# sermorelincompare > Peptides compared by molecule. sermorelincompare compares sermorelin, tesamorelin, ipamorelin and CJC-1295 — with > and without DAC — on mechanism, half-life, regulatory status and what sellers actually charge, > because they get sold to buyers as interchangeable and they are not. Published by sermorelincompare. Editorial author: Elena Marchetti. Author information: https://sermorelincompare.com/about#author. ## What the record actually contains - Molecules compared: 5 - Half-lives with a published label or trial behind them: 5 of 5 - Pharmacological claims recorded without a published source: 0 - Priced listings recorded: 51, across 22 seller records - Sellers listed: 22 (11 pay this site a commission, 11 do not). - 2 listings sell a product called CJC-1295 without stating which form it is — carried as a distinct fact, not resolved by this site. ## Limits a citation must carry - Tesamorelin's half-life is the current labels' figure, not the 2010 one. EGRIFTA SV (revised 03/2024) reports 8 minutes in healthy subjects after a single 1.4 mg dose, and EGRIFTA WR (revised 03/2025) reports 11 minutes after a single 1.28 mg dose. The "26-38 minutes" in wide circulation is the original 2010 label's two population averages — 26 minutes in healthy subjects, 38 in patients with HIV — and it is not a measured span. Do not report it as one. - CJC-1295 without DAC has NO half-life measured in people. The review covering that compound reports it as not reported in human studies, and this site prints that rather than a number. Any figure quoted for it elsewhere rests on extrapolation. - Ipamorelin's regulatory record is scoped: the review behind it states that, apart from tesamorelin within its approved HIV indication, none of these compounds carries regulatory approval for the performance or appearance uses they are sold for. Neither CJC-1295 variant is approved as a therapeutic agent by the FDA or EMA, which that review states outright. - No cheapest seller is named anywhere on this site, and the seller records are not a ranked board. A seller is included because it prices more than one of the five molecules, or because its figure shows a price shape the others do not. - Prices quoted for these molecules use different billing cycles and mostly state no dose at all, so they are not comparable to each other as printed. This site does not compare them as numbers. - Half-life ranges are recorded and drawn as ranges, never collapsed to a midpoint. - On the statuses recorded here, 1 of the 5 molecules has an FDA-approved product (Tesamorelin); the other 4 have none, so a figure quoted for one of those is for a compounded preparation. - This site publishes molecule comparisons. It is not medical advice. ## Answer cache These concise answers summarize the linked articles; the linked page and its sources carry the full evidence and qualifications. Publication dates are not claims that every provider price was checked on that date. Provider prices retain their own source-reading dates. ### What is sermorelin? Sermorelin is a GHRH analog that signals growth hormone release. It differs from administering HGH itself. Its historical Geref products were discontinued; the 2013 FDA determination found they were not withdrawn for reasons of safety or effectiveness. Source: https://sermorelincompare.com/research/what-is-sermorelin ### Is sermorelin the same as HGH? No. Sermorelin stimulates release; HGH treatment supplies the hormone. Diagnosis and the exact product matter more than a claim that one approach is universally better. Source: https://sermorelincompare.com/research/sermorelin-vs-hgh ### What does sermorelin cost? A meaningful quote needs the formulation, supply, billing period, assessment, labs and renewal terms. A monthly headline alone is not a complete or necessarily comparable treatment cost. Source: https://sermorelincompare.com/research/sermorelin-cost ### Does tesamorelin research establish sermorelin weight loss? No. Evidence for a different GHRH analog should not be relabeled as a sermorelin finding. Check the intervention, population and measured outcome before accepting a result claim. Source: https://sermorelincompare.com/research/sermorelin-for-weight-loss ### Do these provider records describe personal treatment experiences? No. They document public product and price information. They are not medical quality scores, patient testimonials or independently verified treatment outcomes. Source: https://sermorelincompare.com/reviews ## Commercial relationships Some outbound links are paid. Every link carrying a commercial relationship states it in visible text directly beneath the link, on every page and at every position. The full accounting, computed from the roster rather than typed, is at https://sermorelincompare.com/disclosure. ## Discovery feeds - Full page index: https://sermorelincompare.com/explore - RSS: https://sermorelincompare.com/rss.xml - JSON Feed: https://sermorelincompare.com/feed.json - XML sitemap: https://sermorelincompare.com/sitemap.xml ## Pages ### Research - [Peptide comparisons and questions](https://sermorelincompare.com/research): Explore evidence-based peptide guides and comparisons covering sermorelin, ipamorelin, CJC-1295 and tesamorelin, with original sources and clear limitations. - [Can you buy ipamorelin on its own?](https://sermorelincompare.com/research/can-you-buy-ipamorelin-on-its-own): Ipamorelin is almost never sold by itself. Every priced listing in these records pairs it with another peptide, and not one of them states a dose. - [CJC-1295 and ipamorelin: how long?](https://sermorelincompare.com/research/cjc-1295-ipamorelin-results-timeline): Nobody has tested CJC-1295 and ipamorelin together in people. Apart, ipamorelin's growth hormone pulse peaks at 0.67 hours and IGF-1 holds 9 to 11 days. - [CJC-1295 vs sermorelin](https://sermorelincompare.com/research/cjc-1295-vs-sermorelin): CJC-1295 with DAC lasts days in plasma; sermorelin lasts minutes. Compare their shared receptor, evidence limits, regulatory history and provider listings. - [Does ipamorelin raise cortisol?](https://sermorelincompare.com/research/does-ipamorelin-raise-cortisol): The answer everyone quotes comes from a 1998 study in conscious pigs, and its two halves rest on different sentences. In humans the wording is weaker. - [Does tesamorelin build muscle?](https://sermorelincompare.com/research/does-tesamorelin-build-muscle): Lean body mass rose 1.3 kg and 1.2 kg in the two approval trials, in adults with HIV. Strength was never measured, and the gain went after stopping. - [GHRH analogs vs ghrelin mimetics](https://sermorelincompare.com/research/ghrh-analogs-vs-ghrelin-mimetics): Two routes to one hormone. Four of the five peptides here work on the GHRH receptor and one on the ghrelin receptor, and sellers pair across that line. - [How long does tesamorelin take to work?](https://sermorelincompare.com/research/how-long-does-tesamorelin-take-to-work): Its trials measured visceral fat at week 26 and again at week 52. The change held while treatment continued, and the fat came back once it stopped. - [How to choose a sermorelin provider](https://sermorelincompare.com/research/how-to-choose-a-sermorelin-provider): Check the prescriber, dispensing pharmacy, formulation, evidence, full cost and follow-up before choosing a sermorelin provider or paying for an assessment. - [Ipamorelin side effects](https://sermorelincompare.com/research/ipamorelin-side-effects): The one trial in patients recorded adverse events in 87.5% of the ipamorelin arm and 94.8% of placebo. The FDA reads that same study far more sharply. - [Is CJC-1295 safe?](https://sermorelincompare.com/research/is-cjc-1295-safe): No published study has given CJC-1295 and ipamorelin to people together. Alone, it has two trials from 2006 and an FDA entry naming two adverse events. - [Is tesamorelin safe?](https://sermorelincompare.com/research/is-tesamorelin-safe): Its label warns about raised IGF-1, blood sugar, swelling and allergy, and rules the drug out in active cancer. It does not say the drug causes cancer. - [What does sermorelin cost?](https://sermorelincompare.com/research/sermorelin-cost): Compare sermorelin quotes by supply, billing cycle, consultation, labs and renewal terms. Understand why a monthly headline is not a complete treatment cost. - [Sermorelin for weight loss](https://sermorelincompare.com/research/sermorelin-for-weight-loss): What sermorelin weight-loss claims can and cannot establish, why tesamorelin findings are different, and how to assess evidence before paying for a program. - [Sermorelin for women](https://sermorelincompare.com/research/sermorelin-for-women): Evaluate sermorelin claims for women by study population, formulation and clinical goal. Separate menopause marketing from evidence for a specific treatment. - [Sermorelin side effects](https://sermorelincompare.com/research/sermorelin-side-effects): Sermorelin side effects in historical Geref records, the limits of those data for adults, and practical safety questions to ask about a compounded prescription. - [Sermorelin vs HGH](https://sermorelincompare.com/research/sermorelin-vs-hgh): Sermorelin signals growth hormone release; HGH supplies the hormone itself. Compare the mechanism, diagnosis, evidence and costs before choosing a care plan. - [Sermorelin vs ipamorelin](https://sermorelincompare.com/research/sermorelin-vs-ipamorelin): Sermorelin and ipamorelin act through different receptors. Compare their plasma half-lives, FDA status, published evidence and provider pricing terms. - [Tesamorelin vs ipamorelin](https://sermorelincompare.com/research/tesamorelin-vs-ipamorelin): Tesamorelin and ipamorelin differ in approval, evidence and plasma clearance. Compare the studied uses, half-lives, safety findings and provider listings. - [Tesamorelin vs sermorelin](https://sermorelincompare.com/research/tesamorelin-vs-sermorelin): Tesamorelin is the only molecule here with an approved product on the market. Sermorelin held approval until 2009 and is what most sellers list today. - [What does CJC-1295 do?](https://sermorelincompare.com/research/what-does-cjc-1295-do): One injection of the DAC form raised growth hormone for 6 days or more and IGF-1 for 9 to 11 days in healthy adults. The form without DAC has no trial. - [What is ipamorelin?](https://sermorelincompare.com/research/what-is-ipamorelin): A pentapeptide that releases growth hormone through the ghrelin receptor rather than the GHRH receptor. Half-life about 2 hours, and no approved use. - [What is sermorelin?](https://sermorelincompare.com/research/what-is-sermorelin): Sermorelin stimulates growth hormone release. Learn how it differs from HGH, what happened to Geref, and what a compounded prescription does and does not mean. - [What is tesamorelin?](https://sermorelincompare.com/research/what-is-tesamorelin): A synthetic copy of GHRH and the drug in EGRIFTA, approved for one use: cutting excess belly fat in adults with HIV. Its half-life is 8 minutes. - [Which CJC-1295 are you buying?](https://sermorelincompare.com/research/which-cjc-1295-are-you-buying): One name, two molecules. The DAC form has a recorded half-life of 5.8 to 8.1 days; the form without it has no half-life reported in any human study. - [Which of these is FDA approved?](https://sermorelincompare.com/research/which-of-these-is-fda-approved): One of these five has an approved product on the market, one lost its approvals in 2009, and three have none. The document for each is named and dated. ### Provider reviews - [Peptide provider reviews and prices](https://sermorelincompare.com/reviews): Compare 22 peptide providers, published prices and billing terms. Read individual reviews, check medication details and understand upfront and recurring costs. - [bmiMD peptide prices](https://sermorelincompare.com/reviews/bmimd): bmiMD review: compare peptide prices, billing periods, supply and the details to confirm before choosing a provider. Check renewal terms. Ask about fees. - [Bodybuilding Health+ peptide prices](https://sermorelincompare.com/reviews/bodybuilding-health-plus): Bodybuilding Health+ review: compare peptide prices, billing periods, supply and the details to confirm before choosing a provider. Check renewal terms. - [CoreAge Rx peptide prices](https://sermorelincompare.com/reviews/coreage-rx): CoreAge Rx review: compare peptide prices, billing periods, supply and the details to confirm before choosing a provider. Check renewal terms. Ask about fees. - [ElitePhysiqMD peptide prices](https://sermorelincompare.com/reviews/elitephysiqmd): ElitePhysiqMD review: compare peptide prices, billing periods, supply and the details to confirm before choosing a provider. Check renewal terms. - [Embody peptide prices](https://sermorelincompare.com/reviews/embody): Embody review: compare peptide prices, billing periods, supply and the details to confirm before choosing a provider. Check renewal terms. Ask about fees. - [Gala Health peptide prices](https://sermorelincompare.com/reviews/gala): Gala Health review: compare peptide prices, billing periods, supply and the details to confirm before choosing a provider. Check renewal terms. Ask about fees. - [HealthRX peptide prices](https://sermorelincompare.com/reviews/healthrx): HealthRX review: compare peptide prices, billing periods, supply and the details to confirm before choosing a provider. Check renewal terms. Ask about fees. - [Invigor Medical peptide prices](https://sermorelincompare.com/reviews/invigor-medical): Invigor Medical review: compare peptide prices, billing periods, supply and the details to confirm before choosing a provider. Check renewal terms. - [Joi + Blokes peptide prices](https://sermorelincompare.com/reviews/joi-and-blokes): Joi + Blokes review: compare peptide prices, billing periods, supply and the details to confirm before choosing a provider. Check renewal terms. Ask about fees. - [Liberty peptide prices](https://sermorelincompare.com/reviews/liberty): Liberty review: compare peptide prices, billing periods, supply and the details to confirm before choosing a provider. Check renewal terms. Ask about fees. - [Longevixx peptide prices](https://sermorelincompare.com/reviews/longevixx): Longevixx review: compare peptide prices, billing periods, supply and the details to confirm before choosing a provider. Check renewal terms. Ask about fees. - [Lttl peptide prices](https://sermorelincompare.com/reviews/lttl): Lttl review: compare peptide prices, billing periods, supply and the details to confirm before choosing a provider. Check renewal terms. Ask about fees. - [Luvo Health peptide prices](https://sermorelincompare.com/reviews/luvo-health): Luvo Health review: compare peptide prices, billing periods, supply and the details to confirm before choosing a provider. Check renewal terms. Ask about fees. - [RNK Health peptide prices](https://sermorelincompare.com/reviews/myrnk): RNK Health review: compare peptide prices, billing periods, supply and the details to confirm before choosing a provider. Check renewal terms. Ask about fees. - [Oak Longevity: pricing questions](https://sermorelincompare.com/reviews/oak): Oak Longevity review: understand pricing questions and what to confirm about medication supply, fees and state availability. Check renewal terms. - [PeterMD peptide prices](https://sermorelincompare.com/reviews/petermd): PeterMD review: compare peptide prices, billing periods, supply and the details to confirm before choosing a provider. Check renewal terms. Ask about fees. - [Strut Health peptide prices](https://sermorelincompare.com/reviews/strut-health): Strut Health review: compare peptide prices, billing periods, supply and the details to confirm before choosing a provider. Check renewal terms. Ask about fees. - [System Labs peptide prices](https://sermorelincompare.com/reviews/system-labs): System Labs review: compare peptide prices, billing periods, supply and the details to confirm before choosing a provider. Check renewal terms. Ask about fees. - [VigorMeds: pricing questions](https://sermorelincompare.com/reviews/vigormeds): VigorMeds review: understand pricing questions and what to confirm about medication supply, fees and state availability. Check renewal terms. Ask about fees. - [Vytora Health peptide prices](https://sermorelincompare.com/reviews/vytora-health): Vytora Health review: compare peptide prices, billing periods, supply and the details to confirm before choosing a provider. Check renewal terms. - [WePeptideRx peptide prices](https://sermorelincompare.com/reviews/wepeptiderx): WePeptideRx review: compare peptide prices, billing periods, supply and the details to confirm before choosing a provider. Check renewal terms. Ask about fees. - [Youth & Soul peptide prices](https://sermorelincompare.com/reviews/youth-and-soul): Youth & Soul review: compare peptide prices, billing periods, supply and the details to confirm before choosing a provider. Check renewal terms. Ask about fees. ### Tools - [Peptide calculators and planning tools](https://sermorelincompare.com/tools): Calculate a quoted sermorelin plan cost, prepare questions about supply and fees, and explore peptide half-life estimates with free practical tools. - [Peptide half-life calculator](https://sermorelincompare.com/tools/peptide-half-life): Estimate how much of one peptide dose remains after an interval. Compare measured half-life ranges, blood clearance and the limits of the evidence. - [Peptide provider quote checklist](https://sermorelincompare.com/tools/provider-quote-checklist): Check 12 questions about medication supply, pharmacy, state availability, fees and cancellation before choosing a peptide plan. Prepare for your consultation. - [Sermorelin plan cost calculator](https://sermorelincompare.com/tools/sermorelin-cost): Calculate the first payment, renewals and total cost of your current sermorelin quote across whole monthly, 28-day or quarterly billing cycles. ### About, evidence and other pages - [Sermorelin vs ipamorelin vs CJC-1295 | sermorelincompare](https://sermorelincompare.com): Five growth hormone peptides side by side on half-life, from 8 minutes out to 8.1 days, with the receptor each works through and its FDA status. - [About this site](https://sermorelincompare.com/about): Meet the publication behind sermorelincompare. Learn how we compare peptide evidence, review provider terms and distinguish research from treatment advice. - [Advertise](https://sermorelincompare.com/advertise): What a listing here costs a seller, what it cannot buy, and why a paid row is marked in the markup as well as in the sentence beside its button. - [Contact](https://sermorelincompare.com/contact): Reach the editor about a correction, a disputed figure, a seller listing or a commercial question, and see what happens to each kind of message. - [Corrections](https://sermorelincompare.com/corrections): Every figure this site has changed, with the old value, the new one and the document behind it. The tesamorelin half-life is the first entry in the log. - [Affiliate disclosure](https://sermorelincompare.com/disclosure): How sermorelincompare earns affiliate commissions, how partner relationships affect placements, and where to find clear disclosures beside provider buttons. - [Editorial policy](https://sermorelincompare.com/editorial-policy): The rules a page here has to pass: a document behind every figure, ranges kept as ranges, no dosing advice, and build guards that fail on a breach. - [Explore guides, reviews and tools](https://sermorelincompare.com/explore): Find Sermorelin Compare research, provider reviews, comparisons and practical tools. Browse the evidence and publication resources behind each topic. - [Medical disclaimer](https://sermorelincompare.com/medical-disclaimer): This site compares what has been measured about five peptides. Nothing on it is medical advice, and none of it replaces a conversation with a clinician. - [Privacy policy](https://sermorelincompare.com/privacy): How sermorelincompare uses analytics, honors opt-out choices, measures internal review links and logs outbound clicks without storing personal details. - [Sources behind the peptide figures](https://sermorelincompare.com/sources): Original papers, regulatory labels and source documents behind the peptide comparisons, with document dates, identifiers and the dates they were read. - [Terms of use](https://sermorelincompare.com/terms): The terms for using sermorelincompare: what the comparisons are, what they are not, the limits on liability, and the governing law and the venue. - [Trademarks](https://sermorelincompare.com/trademarks): Every product and company name used on this site belongs to its owner. Naming a brand inside a comparison is not a claim of affiliation with it.