sermorelincomparePeptides compared by molecule

Sermorelin vs ipamorelin

Sold as two flavors of one thing. They are not: different receptors, very different clearance, and only one of them ever held an FDA approval to lose.

Where to buy either

  • CoreAge Rx

    $99 per month

    What it is
    dose not stated
    What it buys
    Sermorelin
    Read
    September 2026
    See CoreAge Rx pricing

    We may be paid if you sign up through this link.

  • ElitePhysiqMD

    $267.30 per month

    What it is
    dose not stated
    What it buys
    Sermorelin
    Read
    September 2026
  • Longevixx

    $249 per month

    What it is
    dose not stated
    What it buys
    Sermorelin
    Read
    September 2026
  • Oak Longevity

    Publishes no figure for these on its own page. The record says what was looked at and when.

Side by side

Attributes down, molecules across, and the table keeps both columns at every screen width — two molecules fit on a phone where five do not.

Every figure below is followed by the document it comes from, and the documents are listed in full at the foot of the page.
AttributeSermorelinSERIpamorelinIPA
MechanismGHRH analog 1ghrelin mimetic 4
Half-life10–20 min 1~2 hours 5
Cortisol / prolactinnot recordedno cortisol or prolactin rise in conscious swine 6In humans: “comparatively minimal activation of other pituitary–adrenal axes in available human studies Dominikowski et al. 2026
FDA statuswithdrawn 2no approval for these uses 3
Reported use200–300 µg once daily, typically before bedtime 3200–300 µg, 2 or 3 injections a day, often with CJC-1295 (no DAC) 3
What sellers publish12 figures read6 standing rates, 4 floors, 1 prepaid total, 1 introductory price — quoted against 7 different billing cycles. 4 of the 12 say what dose the money buys. A floor is where the pricing starts, not what anyone pays. Not a range, because these are not the same measurement.no figure buys it on its own5 listings in these records include it, each one alongside at least one other molecule.

The reported-use row is what people describe doing online, collected in a peer-reviewed review that labels its own table “anthropological/behavioural data, not clinical recommendations”. It is not prescribing information, and it is not what any seller here charges for.

Half-life is the practical difference

Half-life shapes a dosing schedule more than anything else on this page. A molecule cleared in minutes and one cleared in hours aren’t two doses of the same product; they’re two different propositions about how often you inject and how long each injection is doing anything at all. The scale below is the same logarithmic one used on the site’s full five-molecule matrix, deliberately — the distance between these two bars means the same thing here as it does there.

Plasma half-lifeRecorded
Sermorelin
10–20 min
Ipamorelin
~2 hours
SER
IPA
  • SERSermorelin10–20 min
  • IPAIpamorelin~2 hours
Plasma half-life, logarithmic scale, ordered shortest first. The spacing is the point: linear spacing would put both bands drawn here inside one smudge at the left edge. Where a figure is a range the mark is the range; where a single value is recorded the mark is a tick, because a bar there would draw a span nobody measured.

Two receptors, not one

The mechanism row is why the half-life row isn’t the whole story. The two molecules are recorded here under different mechanism classes, and that difference sits upstream of everything else on the page: a comparison that treats them as one input to the same system is pricing two different things against each other.

The selectivity row is where that shows up in a form a buyer can act on. Ipamorelin carries a selectivity claim in these records; sermorelin carries nothing. That means nothing has been published either way, not that sermorelin lacks the property. An unfilled cell is an open question, and it is printed as one rather than left blank for a reader to fill in with an assumption.

Regulatory status

Sermorelin’s status is recorded here as withdrawn and ipamorelin’s as no approval for these uses. Those are different facts and neither is a verdict. Withdrawn describes a product that once held an approval and no longer does. Ipamorelin never had one: the review behind that cell says that apart from tesamorelin in its HIV indication, none of these compounds carries approval for the uses they are sold for. Why sermorelin’s approval ended is not something the record says, and guessing at it would be inventing a history.

What the two statuses have in common is the more immediately useful part. On the statuses as recorded, neither molecule reaches a US buyer as an approved, off-the-shelf product — so whatever you are quoted is being compounded, and who compounds it, at what strength, and under what oversight are questions for the seller and for a clinician who knows your history. Nothing here is medical advice.

Sources

Every figure in the table above comes from one of the documents below, and each is listed with the date printed on it. Corrections are published, dated and signed on the corrections page, and how a figure gets read is on the editorial policy page.

6 documents, in the order the figures above use them. The date on each is the one printed on the document.

  1. Esposito P, Barbero L, Caccia P, Caliceti P, D'Antonio M, Piquet G, Veronese FM. PEGylation of growth hormone-releasing hormone (GRF) analogues. Advanced Drug Delivery Reviews, volume 55, issue 10, pages 1279–1291.Document date: 2003-09-26. PMID 14499707, doi:10.1016/s0169-409x(03)00109-1. Read September 2026.
  2. Food and Drug Administration, Department of Health and Human Services. Determination That GEREF (Sermorelin Acetate) Injection, 0.5 Milligrams Base/Vial and 1.0 Milligrams Base/Vial, and GEREF (Sermorelin Acetate) Injection, 0.05 Milligrams Base/Amp, Were Not Withdrawn From Sale for Reasons of Safety or Effectiveness. Federal Register, volume 78, number 42, pages 14095–14096, Notice.Document date: published 2013-03-04, signed 2013-02-26. 78 FR 14095, FR Doc. 2013-04827, Docket No. FDA-2012-P-1071. Read September 2026.
  3. Dominikowski A, Rękoś Z, Olejarz M, Szczepanek-Parulska E, Domin R, Ruchała M. The emerging landscape of performance-enhancing peptides modulating GH-IGF1 axis: bridging the gap between clinical evidence and patient self-administration. Frontiers in Endocrinology, volume 17, article 1822475.Document date: 2026-06-18. PMID 42395176, PMC13322892, doi:10.3389/fendo.2026.1822475. Read September 2026.
  4. Venkova K, Mann W, Nelson R, Greenwood-Van Meerveld B. Efficacy of ipamorelin, a novel ghrelin mimetic, in a rodent model of postoperative ileus. Journal of Pharmacology and Experimental Therapeutics, volume 329, issue 3, pages 1110–1116.Document date: 2009-06. PMID 19289567, doi:10.1124/jpet.108.149211. Read September 2026.
  5. Gobburu JV, Agersø H, Jusko WJ, Ynddal L. Pharmacokinetic-pharmacodynamic modeling of ipamorelin, a growth hormone releasing peptide, in human volunteers. Pharmaceutical Research, volume 16, issue 9, pages 1412–1416.Document date: 1999-09. PMID 10496658, doi:10.1023/a:1018955126402. Read September 2026.
  6. Raun K, Hansen BS, Johansen NL, Thøgersen H, Madsen K, Ankersen M, Andersen PH. Ipamorelin, the first selective growth hormone secretagogue. European Journal of Endocrinology, volume 139, issue 5, pages 552–561.Document date: 1998-11. PMID 9849822, doi:10.1530/eje.0.1390552. Read September 2026.

What these figures actually are

Every figure on this site for the molecules on this page, with the qualifier that makes it mean something: what kind of number it is, what period it is charged for, what dose it buys, and the day it was read off the seller’s own page. They are grouped by molecule and not ordered by size, because a floor, a standing rate, a prepaid total and an introductory price are four different measurements and putting them in a line would invent a ranking. Nothing here names a cheapest. For the two-form distinction inside CJC-1295 rather than the receptor difference compared here, see CJC-1295 vs sermorelin.

17 priced listings from 11 of the 14 sellers below, quoted against 7 different billing cycles, in the order the records are written — not ranked, not sorted by size, and no cheapest is named, because a floor, a standing rate, a prepaid total and an introductory price are four different measurements. The other 3 sellers are listed with no figure at all; the reason is in the row. Every figure read off the seller's own page, September 2026.

The board scrolls sideways; the seller column and the button column both stay put.

SellerWhat the figure buysFigure, and when it was checkedWhat it isChargedDoseGo
ElitePhysiqMDSermorelinSermorelin$267.30September 2026standing rateper monthdose not statedOpen listing →
TesamorelinIpamorelinTesamorelin / Ipamorelin$274.50September 2026standing rateper monthdose not stated
IpamorelinCJC-1295 + Ipamorelin — also buys CJC-1295, with or without DAC not stated$315.00September 2026standing rateper monthdose not stated
LongevixxSermorelinSermorelinfrom $249September 2026floorper monthdose not statedOpen listing →
IpamorelinCJC-1295 / Ipamorelin — also buys CJC-1295, with or without DAC not statedfrom $329September 2026floorper monthdose not stated
TesamorelinIpamorelinTesamorelin / Ipamorelinfrom $349September 2026floorper monthdose not stated
Oak Longevityno figure we can publishthe two figures render inside the order flow, each struck through and replaced, with a promotional code shown as applied — so what is on screen is a discounted checkout price, not a standing rate anyone is quoted before starting.September 2026Open site →
Youth & SoulSermorelinIpamorelinGrowth Hormone Optimization — also buys NAD+ sublingual tablets (250mg); Methylene Blue; IGF-1 & hormone panel blood work review; physician monitoring & dose optimization$149September 2026standing rateper monthdose not statedOpen listing →
LibertySermorelinSermorelin — 1 Month$116September 2026standing rateper month200–500 µg nightly at bedtime, escalating by phaseOpen listing →
WePeptideRxSermorelinCompounded Sermorelin — 28-Day Supply$249September 2026standing rateper 28-day supply0.75, 2.25 or 3 mg per week — the same price at every doseOpen listing →
SermorelinCompounded Sermorelin — 28-Day Supply$209September 2026standing rateper 28-day supply0.75, 2.25 or 3 mg per week — the same price at every dose; $249 shown struck through beside it
PeterMDSermorelinSermorelin — 4-Week Supply$211.65September 2026standing rateper 4-week supplydose not statedOpen listing →
Joi + BlokesSermorelinSermorelin Peptide Therapy — Subscribe + Save$559September 2026prepaid totalper 12-week supplyinjections or troches; dose not statedOpen listing →
System LabsSermorelinSermorelin$109September 2026introductory pricefirst monthmonthly supply, 9 mgOpen listing →
SermorelinSermorelin$219September 2026standing rateper monthdose not stated
CoreAge RxSermorelinSermorelinfrom $99September 2026floorper monthdose not statedOpen listing →

We may be paid if you sign up through this link.

Invigor MedicalSermorelinSermorelin Injectionsfrom $220September 2026floorcycle not stateddose not statedOpen listing →
Luvo HealthSermorelinSermorelinfrom $27September 2026floorper weekdose not statedOpen listing →
VigorMedsno figure we can publishthe page prints two different floors for the same listing — “from $149 per month” on the product grid and “from $199” on the catalog’s own finder deck, for the same product — and the $50 between them is the size of a “$50 off first order” badge that neither figure says is already applied.September 2026Open listing →
Vytora Healthno figure we can publishthe page contradicts itself: the buy panel and the page's own FAQ give different monthly figures for the same plan, and nothing on the page says which is current.September 2026Open listing →

Read off each seller’s own page and dated in the row. Nothing here is scored or ranked, and the rows are in the order the sellers were read.

Every figure on this site that buys Sermorelin or Ipamorelin on its own — 12 of them, from 10 sellers, on one scale.

US dollars, exactly as each seller prints them — one axis, 7 different billing cycles and 4 different kinds of figure.

  1. ElitePhysiqMD — “Sermorelin”

    $267.30

    a standing rate · per month — dose not stated

  2. Longevixx — “Sermorelin”

    from $249

    a floor, not a rate · per month — dose not stated

  3. Liberty — “Sermorelin — 1 Month”

    $116

    a standing rate · per month — 200–500 µg nightly at bedtime, escalating by phase

  4. WePeptideRx — “Compounded Sermorelin — 28-Day Supply”

    $249

    a standing rate · per 28-day supply — 0.75, 2.25 or 3 mg per week — the same price at every dose

  5. WePeptideRx — “Compounded Sermorelin — 28-Day Supply”

    $209

    a standing rate · per 28-day supply — 0.75, 2.25 or 3 mg per week — the same price at every dose; $249 shown struck through beside it

  6. PeterMD — “Sermorelin — 4-Week Supply”

    $211.65

    a standing rate · per 4-week supply — dose not stated

  7. Joi + Blokes — “Sermorelin Peptide Therapy — Subscribe + Save”

    $559

    a total, paid up front · per 12-week supply — injections or troches; dose not stated

  8. System Labs — “Sermorelin”

    $109

    an introductory price · first month — monthly supply, 9 mg

  9. System Labs — “Sermorelin”

    $219

    a standing rate · per month — dose not stated

  10. CoreAge Rx — “Sermorelin”

    from $99

    a floor, not a rate · per month — dose not stated

  11. Invigor Medical — “Sermorelin Injections”

    from $220

    a floor, not a rate · cycle not stated — dose not stated

  12. Luvo Health — “Sermorelin”

    from $27

    a floor, not a rate · per week — dose not stated

12 single-molecule figures recorded from 10 sellers’ own pages, each with the date it was read, on the seller records.

Where each one is sold

3 of this site’s 14 seller records carry more than one of Sermorelin, Ipamorelin — which is the only reason they are listed here rather than everyone we have read. Their figures, with every qualifier attached, are in the board above. Some sellers here pay us a commission; it does not change who is listed or what their figure says — how we earn.

ElitePhysiqMD

Prices four listings across three of these molecules on one catalog page and states a dose on none of them. Tesamorelin alone and tesamorelin with ipamorelin carry the identical figure, which is the clearest thing on the page: adding a second molecule changes the price by nothing. The catalog also prints “Save 10% with subscription” beside the figures.

Longevixx

Every figure on this catalog is a floor — the page prints “from” in front of all of them — and none states a dose, so the gaps between the four are gaps between starting points, not between what anyone pays. The CJC-1295 listing is sold only as a pairing and never says which form of CJC-1295 it contains.

Youth & Soul

Sells a tier, not a drug. The figure buys sermorelin and ipamorelin together with the other items listed against it, so it is not a price for either peptide and is not used as one here. Neither molecule is offered on its own anywhere on the page.