The closest pair here: same class, both gone from the blood in minutes, both sold off the same telehealth menus. What separates them is the paperwork — one has an FDA-approved product on the market and the other had one and lost it — and the shelves have gone almost entirely the other way.
Where to buy either
CoreAge Rx
$99 per month
We may be paid if you sign up through this link.
ElitePhysiqMD
$267.30 per month
Longevixx
$249 per month
Oak Longevity
Publishes no figure for these on its own page. The record says what was looked at and when.
Tesamorelin is recorded here as approved (Egrifta SV) and Sermorelin as withdrawn. Those are two different facts and the difference matters: sermorelin is not a molecule that was never approved. It held approvals, and they were withdrawn in 2009 after the products were discontinued — the Federal Register notice says the withdrawal was not for reasons of safety or effectiveness. “Never approved” would be false about it, and “withdrawn” is the word the record supports.
What that leaves is a live approval on one side and a lapsed one on the other. Neither of those tells you which molecule is right for anybody. An unapproved molecule is not thereby a bad one and an approved one is not thereby better for you — the status is a fact about a regulatory record, and interpreting it for your situation is a clinician’s job. What the approved product is for, and who was in the trials behind it, is on what is tesamorelin.
Neither of these lasts long. Sermorelin is recorded at 10–20 min and Tesamorelin at 8 min in healthy subjects, one 1.4 mg dose of EGRIFTA SV. On the axis below they sit almost on top of each other, at the far left of a scale whose right-hand end is measured in days.
The tesamorelin figure is worth a second look, because the number you meet elsewhere is usually a different one. The original EGRIFTA label, revised 11/2010, reported 26 minutes in healthy subjects and 38 in patients with HIV; the two current labels report 8 min and 11 minutes in healthy subjects after single dose subcutaneous administration of the 1.28 mg of EGRIFTA WR. What circulates as “26 to 38 minutes” is the older label’s two populations read as one span. What is tesamorelin sets the three labels side by side.
For a buyer the practical consequence is the same either way: both of these are daily injections, and the reason is not that the drug hangs around. It is what the drug sets off, which is measured in the days after the dose rather than the minutes.
Attributes down, molecules across, both columns kept at every screen width. A cell reading “not recorded” is a statement about this site’s records rather than a claim about the molecule, and it takes no citation marker for that reason — what would settle it is us doing the work, not a reference.
| Attribute | TesamorelinTES | SermorelinSER |
|---|---|---|
| Mechanism | GHRH analog 1 | GHRH analog 4 |
| Half-life | 8 min 2EGRIFTA WR label: “11 minutes in healthy subjects after single dose subcutaneous administration of the 1.28 mg of EGRIFTA WR” EGRIFTA WR label, revised 03/2025 | 10–20 min 4 |
| Cortisol / prolactin | not recorded | not recorded |
| FDA status | approved (Egrifta SV) 2 | withdrawn 5 |
| Reported use | 2 mg once daily 1 | 200–300 µg once daily, typically before bedtime 1 |
| What sellers publish | 2 figures read1 standing rate, 1 floor — quoted against 1 billing cycle. 0 of the 2 say what dose the money buys. A floor is where the pricing starts, not what anyone pays. Not a range, because these are not the same measurement. | 12 figures read6 standing rates, 4 floors, 1 prepaid total, 1 introductory price — quoted against 7 different billing cycles. 4 of the 12 say what dose the money buys. A floor is where the pricing starts, not what anyone pays. Not a range, because these are not the same measurement. |
The reported-use row is what people describe doing online, collected in a peer-reviewed review that labels its own table “anthropological/behavioural data, not clinical recommendations”. It is not prescribing information, and it is not what any seller here charges for.
This is the part a comparison of two molecules does not show you. 14 of the 14 sellers whose pages here list sermorelin. 3 list tesamorelin. The molecule with the live approval is on 3 of 14 of these menus; the one whose approval lapsed is on every one of them.
This site does not know why, and it is not going to guess: nothing in these records says anything about cost of goods, prescribing patterns, or what a compounder can obtain. What the records do say is what is on the shelves that were read, on the dates recorded beside each figure — and on those shelves the approved molecule is the rare one.
Sellers listing Sermorelin
14 of 14
12 of the site's figures buy it on its own, against 7 different billing cycles.
Sellers listing Tesamorelin
3 of 14
2 figures buy it on its own; a further 2 name it inside a pairing.
Tesamorelin figures that state a dose
0 of 2
Not one of them. The literature records 2 mg once daily as the reported use, and there is nothing here to check that against.
Sermorelin figures that state a dose
4 of 12
The molecule with the deeper roster is also the only one of the two with any stated dose at all.
Counted from the 14 records behind the board, every figure read off the seller’s own page and dated. The per-seller working is on the seller records.
Every figure on this site for these two molecules, with the qualifier that makes it mean something: what kind of number it is, what period it is charged for, what dose it buys, and the day it was read. Grouped by molecule, not ordered by size — a floor, a standing rate, a prepaid total and an introductory price are four different measurements. Nothing here names a cheapest.
The board scrolls sideways; the seller column and the button column both stay put.
| Seller | What the figure buys | Figure, and when it was checked | What it is | Charged | Dose | Go |
|---|---|---|---|---|---|---|
| ElitePhysiqMD | Sermorelin“Sermorelin” | $267.30September 2026 | standing rate | per month | dose not stated | Open listing → |
| Tesamorelin“Tesamorelin” | $274.50September 2026 | standing rate | per month | dose not stated | ||
| TesamorelinIpamorelin“Tesamorelin / Ipamorelin” | $274.50September 2026 | standing rate | per month | dose not stated | ||
| Longevixx | Sermorelin“Sermorelin” | from $249September 2026 | floor | per month | dose not stated | Open listing → |
| Tesamorelin“Tesamorelin” | from $299September 2026 | floor | per month | dose not stated | ||
| TesamorelinIpamorelin“Tesamorelin / Ipamorelin” | from $349September 2026 | floor | per month | dose not stated | ||
| Oak Longevity | no figure we can publishthe two figures render inside the order flow, each struck through and replaced, with a promotional code shown as applied — so what is on screen is a discounted checkout price, not a standing rate anyone is quoted before starting.September 2026 | Open site → | ||||
| Youth & Soul | SermorelinIpamorelin“Growth Hormone Optimization” — also buys NAD+ sublingual tablets (250mg); Methylene Blue; IGF-1 & hormone panel blood work review; physician monitoring & dose optimization | $149September 2026 | standing rate | per month | dose not stated | Open listing → |
| Liberty | Sermorelin“Sermorelin — 1 Month” | $116September 2026 | standing rate | per month | 200–500 µg nightly at bedtime, escalating by phase | Open listing → |
| WePeptideRx | Sermorelin“Compounded Sermorelin — 28-Day Supply” | $249September 2026 | standing rate | per 28-day supply | 0.75, 2.25 or 3 mg per week — the same price at every dose | Open listing → |
| Sermorelin“Compounded Sermorelin — 28-Day Supply” | $209September 2026 | standing rate | per 28-day supply | 0.75, 2.25 or 3 mg per week — the same price at every dose; $249 shown struck through beside it | ||
| PeterMD | Sermorelin“Sermorelin — 4-Week Supply” | $211.65September 2026 | standing rate | per 4-week supply | dose not stated | Open listing → |
| Joi + Blokes | Sermorelin“Sermorelin Peptide Therapy — Subscribe + Save” | $559September 2026 | prepaid total | per 12-week supply | injections or troches; dose not stated | Open listing → |
| System Labs | Sermorelin“Sermorelin” | $109September 2026 | introductory price | first month | monthly supply, 9 mg | Open listing → |
| Sermorelin“Sermorelin” | $219September 2026 | standing rate | per month | dose not stated | ||
| CoreAge Rx | Sermorelin“Sermorelin” | from $99September 2026 | floor | per month | dose not stated | Open listing → We may be paid if you sign up through this link. |
| Invigor Medical | Sermorelin“Sermorelin Injections” | from $220September 2026 | floor | cycle not stated | dose not stated | Open listing → |
| Luvo Health | Sermorelin“Sermorelin” | from $27September 2026 | floor | per week | dose not stated | Open listing → |
| VigorMeds | no figure we can publishthe page prints two different floors for the same listing — “from $149 per month” on the product grid and “from $199” on the catalog’s own finder deck, for the same product — and the $50 between them is the size of a “$50 off first order” badge that neither figure says is already applied.September 2026 | Open listing → | ||||
| Vytora Health | no figure we can publishthe page contradicts itself: the buy panel and the page's own FAQ give different monthly figures for the same plan, and nothing on the page says which is current.September 2026 | Open listing → | ||||
Read off each seller’s own page and dated in the row. Nothing here is scored or ranked, and the rows are in the order the sellers were read.
US dollars, exactly as each seller prints them — one axis, 7 different billing cycles and 4 different kinds of figure.
ElitePhysiqMD — “Sermorelin”
$267.30
a standing rate · per month — dose not stated
ElitePhysiqMD — “Tesamorelin”
$274.50
a standing rate · per month — dose not stated
Longevixx — “Sermorelin”
from $249
a floor, not a rate · per month — dose not stated
Longevixx — “Tesamorelin”
from $299
a floor, not a rate · per month — dose not stated
Liberty — “Sermorelin — 1 Month”
$116
a standing rate · per month — 200–500 µg nightly at bedtime, escalating by phase
WePeptideRx — “Compounded Sermorelin — 28-Day Supply”
$249
a standing rate · per 28-day supply — 0.75, 2.25 or 3 mg per week — the same price at every dose
WePeptideRx — “Compounded Sermorelin — 28-Day Supply”
$209
a standing rate · per 28-day supply — 0.75, 2.25 or 3 mg per week — the same price at every dose; $249 shown struck through beside it
PeterMD — “Sermorelin — 4-Week Supply”
$211.65
a standing rate · per 4-week supply — dose not stated
Joi + Blokes — “Sermorelin Peptide Therapy — Subscribe + Save”
$559
a total, paid up front · per 12-week supply — injections or troches; dose not stated
System Labs — “Sermorelin”
$109
an introductory price · first month — monthly supply, 9 mg
System Labs — “Sermorelin”
$219
a standing rate · per month — dose not stated
CoreAge Rx — “Sermorelin”
from $99
a floor, not a rate · per month — dose not stated
Invigor Medical — “Sermorelin Injections”
from $220
a floor, not a rate · cycle not stated — dose not stated
Luvo Health — “Sermorelin”
from $27
a floor, not a rate · per week — dose not stated
14 single-molecule figures recorded from 10 sellers’ own pages, each with the date it was read, on the seller records.
Every pharmacological figure on this page comes from one of the documents below. Seller figures are read off the seller’s own page and carry the date they were read.
5 documents, in the order the figures above use them. The date on each is the one printed on the document.
3 of this site’s 14 seller records carry more than one of Tesamorelin, Sermorelin — which is the only reason they are listed here rather than everyone we have read. Their figures, with every qualifier attached, are in the board above. Some sellers here pay us a commission; it does not change who is listed or what their figure says — how we earn.
Prices four listings across three of these molecules on one catalog page and states a dose on none of them. Tesamorelin alone and tesamorelin with ipamorelin carry the identical figure, which is the clearest thing on the page: adding a second molecule changes the price by nothing. The catalog also prints “Save 10% with subscription” beside the figures.
Every figure on this catalog is a floor — the page prints “from” in front of all of them — and none states a dose, so the gaps between the four are gaps between starting points, not between what anyone pays. The CJC-1295 listing is sold only as a pairing and never says which form of CJC-1295 it contains.
The strongest single illustration on this site of the problem it exists to describe: sermorelin and tesamorelin are offered side by side in one medication picker, at the same struck-through figure and the same discounted figure, over the same supply. Two molecules whose recorded half-lives differ by roughly an order of magnitude, priced as though the choice between them were a flavor.